Fig. 2

Overexpression of LINC00908 suppresses PCa cell proliferation, migration, and invasion while promoting apoptosis. LNCaP cells were treated with oe-LINC00908 or with oe-NC as the control. a The effect of LINC00908 on cell proliferation in each group (×200) detected by EdU assay. b The protein expression of MMP-2 and MMP-9 in cells measured by Western blot analysis, normalized to β-actin. c Cell invasion assessed by Transwell assay (×200). d Cell migration assessed by scratch test. e Cell apoptosis assessed by flow cytometry. f Cell cycle distribution assessed by flow cytometry. *p < 0.05 vs. cells treated with oe-NC. The results were measurement data, expressed as mean ± standard deviation, and the unpaired t-test was used for data between two groups. The cell experiment was repeated three times