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Fig. 6 | Cancer Cell International

Fig. 6

From: LINC00908 negatively regulates microRNA-483-5p to increase TSPYL5 expression and inhibit the development of prostate cancer

Fig. 6

The restoration of LINC00908 hinders PCa tumor growth and reduces the expression of MMP-2 and MMP-9 in vivo. Nude mice with PCa were injected with oe-LINC00908 with oe-NC as the control. a Changes in tumor volume in nude mice bearing overexpression of LINC00908. b MMP-2 and MMP-9 expression in mice determined by Western blot analysis, normalized to β-actin. *p < 0.05 vs. mice injected with oe-NC-transfected cells or un-transfected cells. Data were measurement data, expressed as mean ± standard deviation, and one-way ANOVA was used for data comparisons among multiple groups followed by Tukey’s post hoc test. Repeated measures ANOVA was applied for data comparisons between groups at different time points with Bonferroni’s post hoc test. N = 10

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