Fig. 2

Hyperglycemia promoted GC cell proliferation, migration, invasion and ENO1 expression. a Cell proliferation was detected by CCK-8 assays in AGS and MGC803 cells incubated with different glucose concentrations for 24, 48, 72 and 96 h. b, c The effect of hyperglycemia on GC cell migration and invasion was determined by transwell migration and invasion assays. d, e Western blot analysis and qRT-PCR were used to examine ENO1 expression under different glucose concentrations in GC. *P < 0.05, **P < 0.01, ***P < 0.001