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Fig. 3 | Cancer Cell International

Fig. 3

From: RAD51 is a potential marker for prognosis and regulates cell proliferation in pancreatic cancer

Fig. 3

RAD51 is a downstream target of oncogenic KRAS. a, b KRAS G12D introduction into HEK293T cells increased the transcriptional and protein levels of RAD51. c KRAS expression was silenced in PANC-1 and MiaPaCa-2 cells. d, e KRAS knockdown decreased RAD51 mRNA and protein levels in PANC-1 and MiaPaCa-2 cells. f, g UO126 treatment decreased RAD51 expression in PANC-1 and MiaPaCa-2 cells. h RAD51 expression was positively and significantly correlated with KRAS expression in TCGA-included pancreatic cancer patients

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