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Fig. 2 | Cancer Cell International

Fig. 2

From: LncRNA BCYRN1/miR-490-3p/POU3F2, served as a ceRNA network, is connected with worse survival rate of hepatocellular carcinoma patients and promotes tumor cell growth and metastasis

Fig. 2

BCYRN1 strengthened HCC cells growth, invasion, and migration abilities. a, b The mRNA expression level of BCYRN1 was significantly reduced after transfected with si-BCYRN1, **P < 0.01 vs. control, ##P < 0.01 vs. si-con. c, d The mRNA expression level of BCYRN1 was obviously up-regulated after transfected with pcDNA3.1-BCYRN1, **P < 0.01 vs. control, ##P < 0.01 vs. vector. e The OD values of HepG2 cells were decreased after transfected with si-BCYRN1, **P < 0.01. f The OD values of BEL-7402 cells were increased after transfected with pcDNA3.1-BCYRN1, **P < 0.01. g The clone formation number of HepG2 cells was reduced after depletion of BCYRN1, **P < 0.01. h Overexpression of BCYRN1 elevated BEL-7402 cells colony forming ability, **P < 0.01. i The invaded and migrated cells number of HepG2 cells were significantly reduced after knockdown of BCYRN1, **P < 0.01. j Up-regulation of BCYRN1 enhanced BEL-7402 cells invasion and migration abilities, **P < 0.01

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