Fig. 6

BCYRN1/miR-490-3p promoted HCC cells multiplication and colony formation by up-regulating of POU3F2. a The ascending OD values of HepG2 cells caused by miR-490-3p inhibitor or pcDNA3.1-POU3F2 were suppressed by depletion of BCYRN1, **P < 0.01 vs. control, ^##P < 0.01 vs. miR-490-3p inhibitor, ^&&P < 0.01 vs. POU3F2-OE. b The declining OD values of BEL-7402 induced by miR-490-3p mimic or si-POU3F2 were blocked by overexpression of BCYRN1, **P < 0.01 vs. control, ^##P < 0.01 vs. miR-490-3p mimic, ^&&P < 0.01 vs. si-POU3F2. c The increasing number of HepG2 cells clones induced by miR-490-3p inhibitor or pcDNA3.1-POU3F2 were inhibited by knockdown of BCYRN1, **P < 0.01 vs. control,^##P < 0.01 vs. miR-490-3p inhibitor, ^&&P < 0.01 vs. POU3F2-OE. d The decreasing number of BEL-7402 cells clones caused by miR-490-3p mimic or si-POU3F2 were impeded by up-regulation of BCYRN1, **P < 0.01 vs. control, ^##P < 0.01 vs. miR-490-3p mimic, ^&&P < 0.01 vs. si-POU3F2