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Table 1 Clinical characteristics of the patients with gliomas used for implantation

From: Patient-derived xenografts of different grade gliomas retain the heterogeneous histological and genetic features of human gliomas

Patient ID numberAge rangeSexWHO gradesWHO classificationTumor volume (cm3)IDH1 mutant statusATRX expressionTP53 expressionKi67 (%)1p/19q deletion (%)Xenograft formationa
2016112851–55FIIDiffuse astrocytoma, IDHWT90WTNANA30NAY(P3)
2017031331–35MIIOGD, NOS180MUTNANA3–5NAN
2017062056–60FIIAstrocytoma, IDHMUT27MUT+2NAN
2016110951–55MIIIAnaplastic OGD, NOS90MUTNANA< 5NAN
2017061271–75MIIIAnaplastic OGD, NOS100WT++2029/17Y(P2)
2017081461–65MIIIAnaplastic OGD, IDHMUT-1p/19qc°deleted288MUT++1553/46N
2018012956–60MIIIAnaplastic OGD, NOS93.24WT++1573/57Y(P3)
2018052156–60MIIIAnaplastic OGD, IDHMUT-1p/19qc°deleted180MUT++2027/34Y(P4)
2016122166–70FIVGBM, IDHMUT80MUTNANA30NAN
2017032756–60FIVGBM, IDHWT180WTNANA15NAY(P2)
2017041056–60MIVGBM (relapse), IDHWT120WTNA+20NAY(P6)
2017072461–65MIVGBM, IDHWT78.75WT+301/5Y(P2)
2018031446–50FIVGBM, IDHWT240WT++205/1Y(P2)
2018031966–70MIVGBM, IDHWT180WT++30NAY(P5)
2018040856–60MIVGBM, IDHWT125WT++50NAY(P2)
2018051561–65FIVGBM, IDHWT80WT+7033/45Y(P2)
  1. WT, wild type; MUT, mutant type; −, negative; +, positive; Y, yes; P, propagation number; N, no; NA, not assessed; OGD, oligodendroglioma; GBM, Glioblastoma; M, male; F, female; IDH, isocitrate dehydrogenase
  2. aWhether or not the primary tumor was able to be used to form a xenograft tumor