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Table 2 Successfully established primary glioma PDXs from November 2016 to May 2018

From: Patient-derived xenografts of different grade gliomas retain the heterogeneous histological and genetic features of human gliomas

WHO grades

WHO classification

Cases of established PDXs

PDXs success rate

Latency time (weeks, median range)

II

Diffuse astrocytoma, IDHWT

1

1/3

11

III

Anaplastic OGDs, IDHMUT-1p/19qcodeleted

1

60.00% (3/5)

18 (14–22)

Anaplastic OGDs, NOS

2

IV

GBM, IDHWT

7

87.50% (7/8)

9 (5–22)

Total

 

11

68.75% (11/16)

13 (5–22)

  1. IDH, isocitrate dehydrogenase; WT, wildtype; MUT, mutant; OGD, oligodendroglioma; GBM, Glioblastoma; PDX, patient-derived xenograft