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Fig. 1 | Cancer Cell International

Fig. 1

From: Long noncoding RNA SNHG17 induced by YY1 facilitates the glioma progression through targeting miR-506-3p/CTNNB1 axis to activate Wnt/β-catenin signaling pathway

Fig. 1

SNHG17 was highly expressed in glioma and promoted the process of glioma. a GEPIA database showed that SNHG17 expression was strongly expressed in glioma samples. b RT-qPCR displayed that SNHG17 expression was boosted in glioma tissues and cell lines. c RT-qPCR manifested SNHG17 was effectively knocked down in glioma cells. d CCK-8 assay revealed that cell viability was alleviated by SNHG17 suppression. e Colony formation assay uncovered the number of colonies was decreased as a result of SNHG17 depletion. f EdU assay unveiled that EdU positive cells declined due to SNHG17 silence. g, h Flow cytometry and TUNEL assays both unveiled that cell apoptosis was enhanced by down-regulation of SNHG17. i Western blot assay displayed that the protein level of cell apoptosis-related proteins (cleaved-caspase3, cleaved-caspase9 and Bax) was all increased attributed to SNHG17 deficiency. **P < 0.01

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Cancer Cell International

ISSN: 1475-2867

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