Fig. 2

TSPAN9 can reduce the sensitivity of gastric cancer cells to 5-FU. a AGS cells transfected with a TSPAN9-overexpressing plasmid or empty vector plasmid were treated with 0, 2, 20, or 200 µM 5-FU for 48 h. Cell viability was detected by the MTT assay. b MGC803 cells transfected with TSPAN9-overexpressing plasmid or empty vector plasmid were treated with 0, 2, 20, or 200 µM 5-FU for 48 h. Cell viability was detected by the MTT assay. c AGS/R cells transfected with siTSPAN9 or empty vector plasmid were treated with 0, 2, 20, or 200 µM 5-FU for 48 h. Cell viability was detected by the MTT assay. d MGC803/R cells transfected with siTSPAN9 or empty vector plasmid were treated with 0, 2, 20, or 200 µM 5-FU for 48 h. Cell viability was detected by the MTT assay. *p < 0.05, **p < 0.01; Student’s t test