Fig. 1

TUG1 expression was up-regulated and miR-216b-5p was down-regulated in HCC tissues and cells. a, b The expression levels of TUG1 and miR-216b-5p in 40 pairs of HCC tissues and matched noncancerous tissues were measured by qRT-PCR. c, d The expression levels of TUG1 and miR-216b-5p were analyzed in TCGA datasets of HCC patients. e, f The expression levels of TUG1 and miR-216b-5p in human normal hepatocyte cell line THLE-2 and HCC cell lines HAK-2,Hep3B,Huh7 and LC05 were detected using qRT-PCR. *P < 0.05