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Fig. 9 | Cancer Cell International

Fig. 9

From: RETRACTED ARTICLE: Circ_0008035 contributes to cell proliferation and inhibits apoptosis and ferroptosis in gastric cancer via miR-599/EIF4A1 axis

Fig. 9

EIF4A1 abated the effects of circ_0008035 silencing on iron accumulation, lipid peroxidation and mitochondrial membrane potential in GC cells. HGC-27 and AGS cells were transfected with si-NC, si-circ_0008035, si-circ_0008035 + vector or si-circ_0008035 + EIF4A1 and then treated with or without erastin or RSL3. a, b Total iron level, c, d Fe2+ accumulation, e, f MDA level, g, h lipid ROS level, i, j mitochondrial superoxide concentration and k, l mitochondrial membrane potential in HGC-27 and AGS cells were examined by specific kits. *P < 0.05

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