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Fig. 4 | Cancer Cell International

Fig. 4

From: Down-regulation of LINC00472 promotes osteosarcoma tumorigenesis by reducing FOXO1 expressions via miR-300

Fig. 4

FOXO1 was a direct miR-300 target. a The putative target sequence for miR-300 in the 3′-UTR of FOXO1. b The luciferase activities were detected by luciferase reporter assays. c The expressions of FOXO1 protein levels in MG63 and U2OS cells had transfection with miR-NC and miR-300 mimic. d The expressions of FOXO1 protein levels in MG63 and U2OS cells. *P < 0.001, **P < 0.05 n = 5

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