Fig. 5
From: Breast cancer organoids from a patient with giant papillary carcinoma as a high-fidelity model
Representative images and drug sensitivity of organoids from a giant papillary carcinoma of right breast in a 63-year-old Chinese woman. Scale bar = 200 μm. a Representative images of dose response curves for organoids treated with Tamoxifen, Fulvestrant, Palbociclib, Everolimus, PI3K inhibitor (BKM120). Mean ± SD of results from 3 independent experiments is shown for each drug. b Organoids were grown in 3-D culture and treated with indicated drugs. Over 20 structures were scored for each drug. c Representative images of scored structures: Intact, Semi-disintegrated, and Disintegrated (Disint.)