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Fig. 6 | Cancer Cell International

Fig. 6

From: Effect of nicastrin on hepatocellular carcinoma proliferation and apoptosis through PI3K/AKT signalling pathway modulation

Fig. 6

NCSTN exerts its functions via PI3K/Akt activation. a GSEA-enriched pathways. The P-value was lower than 0.05, and the FDR was lower than 0.25. b Enriched genes of cancer-related pathways. A protein–protein network was constructed using the String database (https://string-db.org). The confidence of the interaction score is greater than 0.990, and the disconnected nodes are hidden. c The phosphorylation levels of the PI3K/Akt signalling pathway were detected by Western blotting. t-PI3K, t-Akt and GAPDH were used as internal references

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