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Fig. 7 | Cancer Cell International

Fig. 7

From: ADAM10 promotes cell growth, migration, and invasion in osteosarcoma via regulating E-cadherin/β-catenin signaling pathway and is regulated by miR-122-5p

Fig. 7

ADAM10 overexpression reversed the inhibition the effect of miR-122-5p on osteosarcoma cells. Cell proliferation was evaluated using CCK-8 assay (a). Cell apoptosis was detected by flow cytometer (b). Cell migration was performed by wound healing assay (c). Cell invasion was detected by transwell assay (d). The expression of ADAM10, MMP-9, Cyclin D1, c-Myc, and Survivin was analyzed by western blot (e). The localization and expression of β-catenin were detected by immunofluorescence assay (f) (*P < 0.05)

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