Fig. 2
From: The histone demethylase JMJD2A promotes glioma cell growth via targeting Akt-mTOR signaling
JMJD2A knockdown reduces glioma cell growth and colony formation. aJMJD2A knockdown with lentivirus-mediated shRNA in U87MG, T98G, and U251 glioma cells. glioma cells were infected with lentivirus expressing sh-Ctrl or sh-JMJD2A for 48 h. (b–d) JMJD2A knockdown represses the proliferation of U87MG (b), T98G (c) and U251 (d) glioma cells. Glioma cells were infected with lentivirus expressing sh-ctrl or sh-JMJD2A and cell number was determined at indicated time points. *p < 0.05, **p < 0.01 vs. sh-ctrl. eJMJD2A knockdown inhibits colony formation of glioma cells. glioma cells with/without JMJD2A knockdown were subjected to colony formation assay. The cells were cultured for 2 weeks and the colony number was determined. **p < 0.01 vs. sh-ctrl