Fig. 3
From: The histone demethylase JMJD2A promotes glioma cell growth via targeting Akt-mTOR signaling
JMJD2A overexpression promotes cell growth and colony formation. a Lentivirus-mediated JMJD2A overexpression in glioma cells. Glioma cells were infected with lentivirus expressing ctrl or JMJD2A for 48 h. bJMJD2A overexpression promotes the proliferation of U87MG glioma cells. U87MG cells were infected with lentivirus expressing ctrl or JMJD2A and cell number was determined at indicated time points. **p < 0.01 vs. ctrl. cJMJD2A overexpression facilitates colony formation of glioma cells. Glioma cells with/without JMJD2A overexpression were subjected to colony formation assay. The cells were cultured for 2 weeks and the colony number was determined. **p < 0.01 vs. ctrl. d Lentivirus-mediated JMJD2A overexpression in NHA cells. NHA cells were infected with lentivirus expressing ctrl or JMJD2A for 48 h. eJMJD2A overexpression promotes the proliferation of NHA cells. NHA cells were infected with lentivirus expressing ctrl or JMJD2A and cell number was determined at indicated time points. **p < 0.01 vs. ctrl. fJMJD2A overexpression facilitates colony formation of NHA cells. NHA cells with/without JMJD2A overexpression were subjected to colony formation assay. The cells were cultured for 2 weeks and the colony number was determined. ***p < 0.001 vs. ctrl