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Fig. 3 | Cancer Cell International

Fig. 3

From: Long non-coding RNA NEAT1/miR-338-3p axis impedes the progression of acute myeloid leukemia via regulating CREBRF

Fig. 3

NEAT1 overexpression refrained cell growth, migration and invasion while facilitated apoptosis of AML cells. a The overexpression efficiency of NEAT1 was assessed through qRT-PCR. b Colony formation assay was administrated for the determination of colony formation in KG-1 and HL-60 cells transfected with NEAT1 or NC. c, d Cell viability was detected by MTT assay. e The apoptosis rate was evaluated using flow cytometry. f, g Western blot was exploited for assaying the protein levels of Cleaved PARP and Cleaved caspase-3. h, i The evaluation of cell migration and invasion abilities was conducted by transwell assay. *P < 0.05

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