Table 2 Subgroup analysis for the association between GHET1 expression and OS
From: Prognostic value of long non-coding RNA GHET1 in cancers: a systematic review and meta-analysis
Subgroups | No. of studies | No. of patients | Pooled HR (95% CI) | PHet | I2 (%) | P value |
|---|---|---|---|---|---|---|
Cancer type | ||||||
Digestive system | 6 | 663 | 1.751 [1.274, 2.408] | 0.844 | 0.0 | 0.001 |
Respiratory system | 2 | 157 | 2.363 [1.515, 3.685] | 0.656 | 0.0 | < 0.001 |
Others | 4 | 294 | 2.377 [1.505, 3.754] | 0.357 | 7.2 | < 0.001 |
Cut-off value | ||||||
Median | 10 | 867 | 2.067 [1.615, 2.646] | 0.802 | 0.0 | < 0.001 |
Others | 2 | 247 | 1.894 [1.096, 3.274] | 0.185 | 43.0 | 0.022 |
Treatments | ||||||
Surgery | 10 | 915 | 1.890 [1.475, 2.420] | 0.899 | 0.0 | < 0.001 |
Others | 2 | 199 | 2.918 [1.698, 5.015] | 0.324 | 0.0 | < 0.001 |
Sample size (n) | ||||||
≤ 80 | 5 | 282 | 2.312 [1.574, 3.394] | 0.725 | 0.0 | < 0.001 |
> 80 | 7 | 832 | 1.906 [1.444, 2.517] | 0.609 | 0.0 | < 0.001 |
NOS score | ||||||
≤ 7 | 6 | 449 | 2.456 [1.602, 3.765] | 0.524 | 0.0 | < 0.001 |
> 7 | 6 | 665 | 1.895 [1.454, 2.470] | 0.850 | 0.0 | < 0.001 |