Skip to main content
Fig. 3 | Cancer Cell International

Fig. 3

From: Herbal melanin inhibits colorectal cancer cell proliferation by altering redox balance, inducing apoptosis, and modulating MAPK signaling

Fig. 3

HM induces ROS-mediated apoptosis in CRC cells. Representative scatter plots showing the percentage of apoptotic cells (lower right) measured using Apopxin in the FL1 channel versus 7-AAD in FL3 after 24 h of treatment with HM tested at 100 µg/ml on HT29 (a) and SW620 (b) cells in comparison to the control, the untreated cells. (c) Effect of NAC (ROS inhibitor) on HT29 cell apoptosis induced by 100 µg/ml of HM after 24 h of exposure. The bar graph shows the percentage of apoptotic cells and the results are presented as mean ± SD of three independent experiments. (***) and (****) signify a statistically significant difference (P < 0.001 and P < 0.0001) compared with the control

Back to article page