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Fig. 1 | Cancer Cell International

Fig. 1

From: miR-125a-5p post-transcriptionally suppresses GALNT7 to inhibit proliferation and invasion in cervical cancer cells via the EGFR/PI3K/AKT pathway

Fig. 1

Overexpression of miR-125a-5p suppresses cell proliferation, invasion and increases cell apoptosis. a Relative expression of miR-125a-5p in cervical cancer tissues in comparison with normal cancer adjacent tissues was analyzed (n = 20). b MiR-125a-5p levels in cervical cancer lines including HeLa, SiHa, Caski and C33A were significantly decreased compared with that in the normal cervical epithelial cells (NCEC). c, d Transfection efficiency of HeLa and Caski cells was detected using RT-qPCR after transfection with miR-125a-5p mimic. e, f Cell proliferation was analyzed using CCK-8 assay after transfecting with NC-mimic or miR-125a-5p mimic for 24 h, 48 h and 72 h. g, i Transwell was used to evaluate cell migration after cells were transfected with miR-125a-5p mimic for 24 h. h, jApoptosis rates of cervical cancer after transfection with miR-125a-5p mimic were detected using Flow cytometry. * P < 0.05, ** P < 0.01

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