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Fig. 1 | Cancer Cell International

Fig. 1

From: Silencing of microRNA-135b inhibits invasion, migration, and stemness of CD24+CD44+ pancreatic cancer stem cells through JADE-1-dependent AKT/mTOR pathway

Fig. 1

miR-135b was highly expressed in PCSCs. a The heat map of top 20 differential miRNA expression in PC miRNA dataset GSE41369 (the abscissa indicated the sample number, the ordinate indicated the differential gene, the histogram at the top right indicated the color scale and each rectangle in the map corresponded to a sample expression value); b The proportion of flow sorting positive cells in PANC-1 cells; C, RT-qPCR was used to detect miR-135b expression in cells; *p < 0.05 vs. the PANC-1 group, #p < 0.05 vs. the CD44+CD24+ group. The measurement data were expressed as mean ± standard deviation. Unpaired student’s t-test was used to compare unpaired data between two groups. One-way ANOVA was applied for comparison among multiple groups, followed by Tukey’s post hoc test. The experiment was repeated 3 times

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