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Fig. 3 | Cancer Cell International

Fig. 3

From: Silencing of microRNA-135b inhibits invasion, migration, and stemness of CD24+CD44+ pancreatic cancer stem cells through JADE-1-dependent AKT/mTOR pathway

Fig. 3

Inhibited miR-135b suppressed tumorigenesis and tumor growth in vivo. a Macroscopic observation of tumor size on 30th day. b measurement of tumor volume in nude mice with vernier caliper. c Determination of tumor mass in nude mice by weighing method; The tumorigenicity and growth of PCSCs were detected by tumor formation in nude mice. n = 6, *p < 0.05 vs. the agomir-NC group, #p < 0.05 vs. the antagomir-NC group; The measurement data were expressed as mean ± standard deviation. One-way ANOVA was applied for comparison among multiple groups, followed by Tukey’s post hoc test. Repeated measurement ANOVA was used to compare the data among multiple groups at different time points, followed by the Bonferroni post hoc test

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