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Table 1 Clinical characteristics of non-M3 AML cohort in the TCGA data set with respect to TNFRSF4 expression

From: Elevated TNFRSF4 gene expression is a predictor of poor prognosis in non-M3 acute myeloid leukemia

 

Total

TNFRSF4 low (Z < 0)

TNFRSF4 high (Z ≥ 0)

p value

TNFRSF4 low vs. high

Fisher exact test

Sex, no. (%)

     

 Female

72

59 (81.9)

13 (18.1)

 

0.092

 Male

85

78 (91.8)

7 (8.2)

  

Age, years (range)

   

0.012

 

 Median

59

57

66.5

  

 Mean

56.0 ± 1.29

54.9 ± 1.38

63.5 ± 3.24

  

WBC count ×109/L

   

0.528

 

 Median

22.2

22.2

25.95

  

 Mean

39.3 ± 3.76

37.0 ± 3.62

54.6 ± 15.93

  

PB blasts, %

   

0.254

 

 Median

72

71

76.5

  

 Mean

68.4 ± 1.51

67.7 ± 1.62

72.7 ± 4.13

  

BM blasts,  %

   

0.06

 

 Median

42

39

58.5

  

 Mean

41.5 ± 2.58

39.5 ± 2.73

54.9 ± 7.32

  

NCCN subtype, no.

    

Vs. favorable

 Favorable

17

17 (100)

0 (0)

  

 Intermediate

92

82 (89.1)

10 (10.9)

 

0.169

 Poor

45

36 (80)

9 (20)

 

0.044

FAB subtype, no.

     

 M0

16

13

3

  

 M1

44

36

8

  

 M2

38

33

5

  

 M4

34

32

2

  

 M5

18

17

1

  

 M6

2

2

0

  

 M7

3

2

1