Table 2 Association of TNFRSF4 expression based on patient mutation status in the TCGA data set according to TNFRSF4 expression
From: Elevated TNFRSF4 gene expression is a predictor of poor prognosis in non-M3 acute myeloid leukemia
Total | TNFRSF4 low (Z < 0) | TNFRSF4 high (Z ≥ 0) | p value | ||
|---|---|---|---|---|---|
MUT vs. WT | Fischer exact test | ||||
FLT3, no. (%) | 0.0102 | 0.111 | |||
MUT | 45 (28.7) | 36 (80.0) | 9 (20.0) | ||
WT | 112 (71.3) | 101 (90.2) | 11 (9.8) | ||
IDH1, no. (%) | 0.6846 | 0.695 | |||
MUT | 16 (10.2) | 15 (93.7) | 1 (6.3) | ||
WT | 141 (89.8) | 122 (86.5) | 19 (13.5) | ||
IDH2, no. (%) | 0.9227 | 0.699 | |||
MUT | 17 (10.8) | 16 (94.1) | 1 (5.9) | ||
WT | 140 (89.2) | 121 (86.4) | 19 (13.6) | ||
RUNX1, no. (%) | 0.0311 | 0.759 | |||
MUT | 28 (17.8) | 24 (85.7) | 4 (14.3) | ||
WT | 129 (82.2) | 113 (87.6) | 16 (12.4) | ||
TET2, no. (%) | 0.6979 | 0.103 | |||
MUT | 15 (9.6) | 11 (73.3) | 4 (26.7) | ||
WT | 142 (90.4) | 126 (88.7) | 16 (11.3) | ||
NRAS, no. (%) | 0.4658 | 1 | |||
MUT | 13 (8.3) | 12 (92.3) | 1 (7.7) | ||
WT | 144 (91.7) | 125 (86.8) | 19 (13.2) | ||
CEBPA, no. (%) | 0.7981 | 1 | |||
MUT | 13 (8.3) | 12 (92.3) | 1 (7.7) | ||
WT | 144 (91.7) | 125 (86.8) | 19 (13.2) | ||
WT1, no. (%) | 0.736 | 0.363 | |||
MUT | 10 (6.4) | 10 (100.0) | 0 (0.0) | ||
WT | 147 (93.6) | 127 (86.4) | 20 (13.6) | ||
DNMT3A, no. (%) | 0.6877 | 0.178 | |||
MUT | 42 (26.8) | 34 (81.0) | 8 (19.0) | ||
WT | 115 (73.2) | 103 (89.6) | 12 (10.4) | ||
NPM1, no. (%) | 0.0024 | 0.439 | |||
MUT | 49 (31.2) | 41 (83.7) | 8 (16.3) | ||
WT | 108 (68.8) | 96 (88.9) | 12 (11.1) | ||
TP53, no. (%) | 0.0118 | 0.026 | |||
MUT | 15 (9.6) | 10 (66.7) | 5 (33.3) | ||
WT | 142 (90.4) | 127 (89.4) | 15 (10.6) | ||