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Table 2 Univariate and multivariate analysis of breast cancer patients on overall survival

From: LncRNA IGBP1-AS1/miR-24-1/ZIC3 loop regulates the proliferation and invasion ability in breast cancer

Variable

Univariate analysis

Multivariate analysis

HR (95% CI)

P

HR (95% CI)

P

Age (≥ 60 vs. < 60 years)

1.033 (0.997–1.062)

0.057

  

Menopause (yes vs. no)

1.107 (0.620–1.875)

0.134

  

Stage (II/III/IV vs. I)

2.726 (1.256–4.789)

0.021

2.035 (1.477–3.329)

0.011

IGBP1-AS1 expression (low vs. high)

3.144 (1.494–6.616)

0.003

3.102 (1.365–6.526)

0.005

Histologic grade (III vs. I/II)

1.373 (0.384–2.513)

0.463

  

Histologic type (lobular vs. ductal)

1.208 (0.507–3.391)

0.601

  

ER (yes vs. no)

0.827 (0.384–2.731)

0.379

  

PR (yes vs. no)

0.595 (0.277–1.982)

0.301

  

HER2 (yes vs. no)

1.282 (0.893–2.191)

0.115

  
  1. Italic values indicate significance of P value (P < 0.05)
  2. ER estrogen receptor, PR progesterone receptor, HER2 human epidermal growth factor receptor 2