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Table 2 Univariate and multivariate Cox analysis of the training cohort

From: Integrated nomogram based on five stage-related genes and TNM stage to predict 1-year recurrence in hepatocellular carcinoma

Recurrence at 1 year

Univariate analysis

Multivariate analysis

HR

95% CI

P-value

HR

95% CI

P-value

Sex

 Female

      

 Male

0.596

0.356–0.996

0.048*

0.670

0.397–1.129

0.132

Age

 < 60

      

 ≥ 60

0.842

0.510–1.391

0.502

   

TNM stage

 I

      

 II

2.011

0.993–4.074

0.052

1.949

0.962–3.949

0.064

 III

3.423

1.909–6.139

< 0.001***

2.911

1.616–5.243

< 0.001***

 IV

5.163

0.688–38.733

0.110

6.424

0.816–50.602

0.077

Histologic grade

 G1

      

 G2

0.983

0.447–2.165

0.967

   

 G3

1.230

0.550–2.751

0.613

   

 G4

1.259

0.334–4.748

0.734

   

RS

 Low

      

 High

3.416

2.041–5.717

< 0.001***

3.199

1.891–5.411

< 0.001***

  1. HR Hazard ratio, CI confidence interval, TNM primary tumor, regional lymph nodes and distant metastasis, RS risk score
  2. *P < 0.05, ***P < 0.001
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