Skip to main content
Fig. 1 | Cancer Cell International

Fig. 1

From: A long non-coding RNA LINC00461-dependent mechanism underlying breast cancer invasion and migration via the miR-144-3p/KPNA2 axis

Fig. 1

Bioinformatics analysis results. Differential analysis was performed on the gene profiles obtained from the TCGA-BRCA dataset, and eventually a 729 DElncRNAs, b 67 DEmiRNAs and c 1866 DEmRNAs were screened as shown in Volcano Plots. d Venn diagram was made to identify the potential target mRNAs among the predicted mRNAs and the 1866 DEmRNAs. e A ceRNA network based on the candidate lncRNAs (diamond), miRNAs (square) and mRNAs (circular) was established, with red representing up-regulated genes and blue representing down-regulated genes. f Survival analysis was performed on the KPNA2 in the TCGA-BRCA dataset. The abscissa refers to time (years), the vertical coordinate refers to overall survival rate, red line refers to high expression and blue line refers to low expression. Each node refers to a death event. Finally, the expression levels of g LINC00461 and h KPNA2 were detected in clinical cancer tissue samples and paired adjacent normal tissue samples

Back to article page