Skip to main content
Fig. 3 | Cancer Cell International

Fig. 3

From: FENDRR suppresses cervical cancer proliferation and invasion by targeting miR-15a/b-5p and regulating TUBA1A expression

Fig. 3

FENDRR regulates CC by modulating miR-15a/b-5p/TUBA1A axis. a Bioinformatics analysis of possible mRNAs sharing binding sites with miR-15a/b-5p. b The expression of selected mRNA by qRT-PCR. c Relevant gene expression after overexpressing FENDRR. d TUBA1A relative expression in CC cells. e Overexpression efficiency test. f, h TUBA1A gain-of-function experiments by CCK-8, colony formation assay and transwell assays. i Coexistence verification of indicated molecules. j Pull down assay detected the PCR product of miR-15a/b-5p. k The interaction among FENDRR, miR-15a/b-5p and TUBA1A was demonstrated by luciferase reporter assay. The putative binding sites from StarBase were also verified. **p < 0.01; n.s. not significant

Back to article page