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Fig. 6 | Cancer Cell International

Fig. 6

From: TUG1/miR-133b/CXCR4 axis regulates cisplatin resistance in human tongue squamous cell carcinoma

Fig. 6

The regulatory effect of miR-133b on CXCR4-mediated cisplatin resistance of TSCC cells. The mRNA and protein levels of CXCR4 a, b, IC50 of cisplatin (c), cell viability d, e, invasion (f) and apoptosis (g) were measured in SCC25/CDDP and CAL27/CDDP cells transfected with si-NC, si-CXCR4, si-CXCR4 + in-miR-NC or in-miR-133b by qRT-PCR, western blot, CCK-8, transwell or flow cytometry, respectively. h The protein abundance of CXCR4 was detected in SCC25/CDDP and CAL27/CDDP cells transfected with si-NC, si-TUG1, si-TUG1 + in-miR-NC or in-miR-133b by western blot. *P < 0.05

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