Fig. 2

Cis-regulatory elements of EIF5A1 and EIF5A2 gene. The EIF5A1 gene contains one NF-kappaB binding site in the promoter region (as demonstrated by ChIP assay) and one putative p53 binding site in the first intron. The promoter region of EIF5A2 gene contains four Gli1 binding sites and three HIF1α binding sites