Fig. 5
From: LncRNA MIR4435-2HG triggers ovarian cancer progression by regulating miR-128-3p/CKD14 axis
MIR4435-2HG overexpression reversed the effects of miR-128-3p upregulation on cell proliferation and apoptosis in OC cells. a The expression of miR-128-3p in SKOV3 and OVCAR3 cells transfected with miR-128-3p mimics, NC mimics, miR-128-3p mimics + MIR4435-2HG or miR-128-3p mimics + Vector was detected by qRT-PCR. b, c Cell proliferation was detected using MTT assay. d The apoptosis of SKOV3 and OVCAR3 cells was measured by flow cytometry. Q1: necrotic cells (AnnexinV-FITC)-/PI+; Q2: late apoptotic or necrotic cells (AnnexinV + FITC) +/PI+; Q3: early apoptotic cells (AnnexinV-FITC) +/PI−; Q4: unstained viable cells (AnnexinV-FITC)-/PI−. *P < 0.05