Fig. 1
From: Hsa_circ_0068307 mediates bladder cancer stem cell-like properties via miR-147/c-Myc axis regulation
Hsa_circ_0068307 is expressed at high levels in BCa and exerts oncogenic effects in the BCa cell lines T24 and UMUC3. a Rt-qPCR detection showing the expression of hsa_circ_0068307 in tumor tissues and adjacent normal tissues. Data are presented as the mean ± SD. ***P < 0.001. b Rt-qPCR detection showing the expression of hsa_circ_0068307 in SV-HUC-1 and BCa cell lines. Data are presented as the mean ± SD. ***P < 0.001 vs. SV-HUC-1. c The expression of hsa_circ_0068307 was detected in T24 and UMUC-3 cells transfected with siRNA hsa_circ_0068307 (si-circRNA) or negative control (NC). Data are presented as the mean ± SD. ***P < 0.001 vs. NC. d, e CCK8 detection showing that hsa_circ_0068307 knockdown suppressed cell proliferation in T24 (d) and UMUC-3 (e) cells. Data are presented as the mean ± SD. ***P < 0.001 vs. NC. f, g Colony formation assays showing the proliferation of T24 and UMUC3 cells after knockdown of hsa_circ_0068307. Data are presented as the mean ± SD. ***P < 0.001 vs. NC. h, i Transwell assays showing the migration of BCa cells after knockdown of hsa_circ_0068307. Data are presented as the mean ± SD. ***P < 0.001 vs. NC