Fig. 5
From: Hsa_circ_0068307 mediates bladder cancer stem cell-like properties via miR-147/c-Myc axis regulation
Downregulation hsa_circ_0068307 suppresses tumor growth in nude mouse xenografts. a Representative photographs of T24 tumor formation in xenografts of nude mice. n = 6 per group. b Summary of tumor volumes in mice measured every week. Data are presented as the mean ± SD. **P < 0.01, ***P < 0.001 vs. NC. c Tumor weight was measured after 30 days of injection. Data are presented as the mean ± SD. ***P < 0.001 vs. NC. d qRT-PCR assay showing the expression of miR-147. Data are presented as the mean ± SD. ***P < 0.001 vs. control. e Western blot analysis of the expression of c-Myc and cancer stem cell-related proteins OCT-4, Sox-2, and NANOG in tumor tissues. Data are presented as the mean ± SD. ***P < 0.001 vs. NC