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Table 2 Overall meta-analysis and publication bias data

From: Association of human XPA rs1800975 polymorphism and cancer susceptibility: an integrative analysis of 71 case–control studies

Models

Study number (case/control)

Heterogeneity

Association

Bias

I2

Pa

Fixed/Random

OR (95% CI)

z

Pb

Pc

Pd

Allelic model (G vs. A)

69 (19,039/29,707)

72.0%

< 0.001

Random

1.07 (1.01–1.13)

2.23

0.026

0.645

0.719

Carrier model (G vs. A)

69 (19,039/29,707)

22.3%

0.056

Fixed

1.04 (1.01–1.08)

2.62

0.009

0.637

0.727

Homozygotic model (GG vs AA)

69 (19,039/29,707)

68.9%

< 0.001

Random

1.12 (1.00–1.25)

1.92

0.054

0.404

0.476

Heterozygotic model (AG vs. AA)

69 (19,039/29,707)

54.2%

< 0.001

Random

1.00 (0.92–1.09)

< 0.01

0.996

0.303

0.215

Dominant model (AG + GG vs. AA)

69 (19,039/29,707)

66.0%

< 0.001

Random

1.05 (0.96–1.15)

1.02

0.307

0.393

0.231

Recessive model (GG vs. AA + AG)

71 (19,257/30,208)

57.5%

< 0.001

Random

1.12 (1.04–1.20)

3.19

0.001

0.481

0.753

  1. OR odds ratio, CI confidence interval, aP-value of Cochrane’s Q statistic for the assessment of heterogeneity, bP-value of association, cP-value of Begg’s test, dP-value of Egger’s test