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Fig. 5 | Cancer Cell International

Fig. 5

From: LncRNA FLVCR1-AS1 promotes proliferation, migration and activates Wnt/β-catenin pathway through miR-381-3p/CTNNB1 axis in breast cancer

Fig. 5

CTNNB1 overexpression rescues the oncogenic function of FLVCR1-AS1. a qRT-PCR analysis was conducted to examine the CTNNB1 expression level BC cell lines and normal cell lines. b qRT-PCR analysis was used to determine the expression of after CTNNB1 transfecting with pcDNA3.1 and pcDNA3.1/CTNNB1 plasmid. c, d qRT-PCR and western blot were performed to study the expression of CTNNB1 mRNA and protein. The bands obtained from western blot analysis were further quantified via Image J. ei Functional experiments were performed on BC cells in rescue analyses. j, k Xenograft tumor growth curve, volume and weight between shCtrl and sh-FLVCR1-AS1 mice groups were compared. **P < 0.01

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