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Fig. 8 | Cancer Cell International

Fig. 8

From: HE4 overexpression decreases pancreatic cancer Capan-1 cell sensitivity to paclitaxel via cell cycle regulation

Fig. 8

HE4 knockdown and Pac treatment affected the expression cell cycle regulators PCNA and p21 in Capan-1 cells. a Representative results of Western blotting with the use of specific antibodies against PCNA, p21, or GAPDH, respectively, in the control, HE4, Pac, and siHE4 + Pac experimental groups. b Densitometry analysis results showing the relative protein levels of PCNA (left panel) or P21 (right panel). c The significant changes of X values for PCNA (left panel) or p21 (right panel) with HE4 knockdown, indicating interactive effects by HE4 knockdown and paclitaxel treatment. *p < 0.05; ** p < 0.01

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