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Fig. 2 | Cancer Cell International

Fig. 2

From: Biological effects of selective COX-2 inhibitor NS398 on human glioblastoma cell lines

Fig. 2

PGE2 levels released by U87MG- and T98G-derived neurospheres. a A representative image of western blot of COX-2 and β-actin proteins in control (CNTR) U87MG and T98G neurospheres. The results of the densitometric analysis of bands expressed as ratio vs β-actin band intensity are showed. Data are representative of three independent experiments, and mean values ± SEM are shown. b PGE2 levels were detected in supernatants from neurospheres after 48 h culture in the presence of NS398 at indicated concentrations. CNTR: control, drug vehicle alone. The results, relative to one representative out of two experiments performed in triplicate, are expressed as mean ± SD. For comparative analysis of groups of data, one-way ANOVA followed by Dunnett post hoc test was used (*p < 0.05, **p < 0.01, ****p < 0.0001 vs CNTR)

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