|
Nestin expression and survival outcomes
|
|
BCSS(U)
|
2.061–2.488
|
1.741–3.357
|
0.060
|
0.065
|
|
BCSS(M)
|
1.240–2.000
|
1.000–3.810
|
1.000
|
–
|
|
OS(U)
|
1.648–2.117
|
1.202–3.386
|
0.260
|
0.018
|
|
OS(M)
|
1.715–2.362
|
0.862–6.474
|
1.000
|
0.536
|
|
DMFS(U)
|
1.040–1.993
|
0.674–3.564
|
1.000
|
–
|
|
RFS(U)
|
2.575–2.640
|
1.150–6.061
|
1.000
|
–
|
|
Nestin expression and clinicopathological parameters
|
|
Age (> 35 vs. < 35)
|
0.375–0.809
|
0.200–2.529
|
1.000
|
0.437
|
|
TNM stage (III vs. I-II)
|
4.051–5.924
|
2.337–10.828
|
0.876
|
0.386
|
|
T stage (T2–4 vs. T1)
|
1.256–1.568
|
1.046–2.097
|
0.917
|
0.340
|
|
N stage (N+ vs. N0)
|
0.893–1.114
|
0.637–1.586
|
0.755
|
0.358
|
|
IDC vs. DCIS
|
1.280–1.477
|
0.428–3.928
|
1.000
|
0.817
|
|
IDC vs. ILC
|
1.927–3.935
|
0.890–10.835
|
0.221
|
0.056
|
|
LVI (positive vs. negative)
|
0.806–1.021
|
0.656–1.505
|
1.000
|
0.484
|
|
BVI (positive vs. negative)
|
2.558–2.683
|
0.936–7.689
|
1.000
|
–
|
|
VPI (high vs. low)
|
2.958–3.043
|
1.650–5.302
|
0.296
|
0.066
|
|
Nestin expression and immunohistochemical markers
|
|
ER (positive vs. negative)
|
0.107–0.134
|
0.064–0.208
|
0.243
|
0.306
|
|
PR (positive vs. negative)
|
0.167–0.218
|
0.105–0.341
|
0.474
|
0.455
|
|
HER2 (positive vs. negative)
|
0.610–0.826
|
0.321–1.268
|
0.013
|
0.068
|
|
Ki-67 (high vs. low)
|
4.998–7.542
|
2.807–14.262
|
0.462
|
0.059
|
|
TNBC vs. Non-TNBC
|
7.898–10.775
|
5.246–18.386
|
0.348
|
0.657
|
|
CK5 (positive vs. negative)
|
7.605–9.786
|
5.983–14.333
|
0.462
|
0.023
|
|
P-cadherin (positive vs. negative)
|
7.440–8.244
|
4.945–12.964
|
0.308
|
0.123
|
|
EGFR (positive vs. negative)
|
6.306–7.034
|
3.962–10.244
|
1.000
|
0.888
|
|
BLP1 (present vs. absent)
|
19.543–23.784
|
11.296–41.447
|
1.000
|
0.629
|
|
BLP2 (present vs. absent)
|
15.339–20.293
|
9.432–33.109
|
0.308
|
0.280
|
|
BLP3 (present vs. absent)
|
12.265–13.134
|
4.821–31.205
|
0.296
|
0.253
|
|
BLP4 (present vs. absent)
|
19.715–23.878
|
9.672–48.403
|
0.296
|
0.468
|
|
BLP5 (present vs. absent)
|
22.230–26.590
|
11.294–53.144
|
1.000
|
0.683
|
|
p53 (positive vs. negative)
|
3.906–5.397
|
2.619–8.421
|
0.221
|
0.055
|
|
FOXA1 (positive vs. negative)
|
0.043–0.241
|
0.009–0.593
|
1.000
|
–
|
