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Table 2 Sensitivity analysis and publication bias

From: Clinicopathological and prognostic significance of nestin expression in patients with breast cancer: a systematic review and meta-analysis

  Sensitivity analysis Publication bias (P value)
HR/OR fluctuation 95% CI fluctuation Begg’s test Egger’s test
Nestin expression and survival outcomes
 BCSS(U) 2.061–2.488 1.741–3.357 0.060 0.065
 BCSS(M) 1.240–2.000 1.000–3.810 1.000
 OS(U) 1.648–2.117 1.202–3.386 0.260 0.018
 OS(M) 1.715–2.362 0.862–6.474 1.000 0.536
 DMFS(U) 1.040–1.993 0.674–3.564 1.000
 RFS(U) 2.575–2.640 1.150–6.061 1.000
Nestin expression and clinicopathological parameters
 Age (> 35 vs. < 35) 0.375–0.809 0.200–2.529 1.000 0.437
 TNM stage (III vs. I-II) 4.051–5.924 2.337–10.828 0.876 0.386
 T stage (T2–4 vs. T1) 1.256–1.568 1.046–2.097 0.917 0.340
 N stage (N+ vs. N0) 0.893–1.114 0.637–1.586 0.755 0.358
 IDC vs. DCIS 1.280–1.477 0.428–3.928 1.000 0.817
 IDC vs. ILC 1.927–3.935 0.890–10.835 0.221 0.056
 LVI (positive vs. negative) 0.806–1.021 0.656–1.505 1.000 0.484
 BVI (positive vs. negative) 2.558–2.683 0.936–7.689 1.000
 VPI (high vs. low) 2.958–3.043 1.650–5.302 0.296 0.066
Nestin expression and immunohistochemical markers
 ER (positive vs. negative) 0.107–0.134 0.064–0.208 0.243 0.306
 PR (positive vs. negative) 0.167–0.218 0.105–0.341 0.474 0.455
 HER2 (positive vs. negative) 0.610–0.826 0.321–1.268 0.013 0.068
 Ki-67 (high vs. low) 4.998–7.542 2.807–14.262 0.462 0.059
 TNBC vs. Non-TNBC 7.898–10.775 5.246–18.386 0.348 0.657
 CK5 (positive vs. negative) 7.605–9.786 5.983–14.333 0.462 0.023
 P-cadherin (positive vs. negative) 7.440–8.244 4.945–12.964 0.308 0.123
 EGFR (positive vs. negative) 6.306–7.034 3.962–10.244 1.000 0.888
 BLP1 (present vs. absent) 19.543–23.784 11.296–41.447 1.000 0.629
 BLP2 (present vs. absent) 15.339–20.293 9.432–33.109 0.308 0.280
 BLP3 (present vs. absent) 12.265–13.134 4.821–31.205 0.296 0.253
 BLP4 (present vs. absent) 19.715–23.878 9.672–48.403 0.296 0.468
 BLP5 (present vs. absent) 22.230–26.590 11.294–53.144 1.000 0.683
 p53 (positive vs. negative) 3.906–5.397 2.619–8.421 0.221 0.055
 FOXA1 (positive vs. negative) 0.043–0.241 0.009–0.593 1.000