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Fig. 4 | Cancer Cell International

Fig. 4

From: LncRNA H19 promotes triple-negative breast cancer cells invasion and metastasis through the p53/TNFAIP8 pathway

Fig. 4

P53 acts as a transcriptional inhibitor of TNFAIP8. a The mRNA (upper) and protein (lower) levels of TNFAIP8 in BT-549 and MDA-MB-231 cells co-transfected with control, beta-gal, p53, siRNA-NC, or p53-siRNA. b Relative luciferase activity in pGL3-TNFAIP8-WT-treated BT-549 and MDA-MB-231 cells co-transfected with pGL4.17, siRNA-NC, p53-siRNA, or p53, respectively. Measurements were carried out in triplicate, and experiments were repeated three times. Data are presented as mean ± SD. * p < 0.05, ** p < 0.01and *** p < 0.001

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