Fig. 3From: Ubiquitin ligase CHAF1B induces cisplatin resistance in lung adenocarcinoma by promoting NCOR2 degradationCHAF1B promote protein ubiquitination degradation of NCOR2. a Immunocoprecipitation showed that CHAF1B interacted with NCOR2. b A schematic diagram of the interaction between CHAF1B and NCOR2. Brown surface: CHAF1B, rainbow cartoon: NCOR2. c Immunofluorescence showed that NCOR2 (green) mainly existed in the nucleus, and CHAF1B (red) existed in both the nucleus and cytoplasm, both of which were co-located in the nucleus. d Protein stability test confirmed that NCOR2 degradation rate slowed down after CHAF1B was knocked down. *p < 0.05, ***p < 0.001Back to article page