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Fig. 5 | Cancer Cell International

Fig. 5

From: FOXC2 is a prognostic biomarker and contributes to the growth and invasion of human hepatocellular carcinoma

Fig. 5

Knockdown of Ang-2 in MHCC-97H and Huh-7 cells with FOXC2 overexpression. Ang-2 knockdown led to impairment of cell proliferation of both MHCC-97H (a) and Huh-7 (b) cells with FOXC2 overexpression. Decreased Ang-2 contributed to impairment of cell migration of both cells with FOXC2 overexpression (c–d). The FOXC2 overexpressing cells with Ang-2 knockdown exhibited decreased cell invasion (e–f). g Western blot assessing Ang-2 levels in MHCC-97H and Huh-7 cells with FOXC2 overexpression and Ang-2 knockdown (KD). Significance at p < 0.01 is denoted by ‘*’ relative to control by student’s t-test

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Cancer Cell International

ISSN: 1475-2867

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