FOXC2 is a prognostic biomarker and contributes to the growth and invasion of human hepatocellular carcinoma

Table 1 Correlation between FOXC2 expression and clinicopathologic

Variable	N	FOXC2 expression		P value
Variable	N	High	Low
Gender				0.301
Male	220	130	90
Female	60	40	20
Age (years)				0.211
< 50	173	100	73
≥ 50	107	70	37
Tumor size (cm)^△				0.000
<5	150	70	80
≥ 5	130	100	30
Serum HBsAg				0.582
Positive	245	147	98
Negative	35	23	12
Serum AFP(ng/ml)				0.460
< 25	157	92	65
≥ 25	123	78	45
Cirrhosis				0.806
Presence	120	74	46
Absence	160	96	64
UICC stage				0.007
I + II	132	69	63
III + IV	148	101	47
Metastasis/Recurrence				0.014
Yes	154	104	50
No	126	66	60
Edmondson grade				0.429
Low (I/II)	192	120	72
High (III/IV)	88	50	38

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