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Table 2 Cox regression analysis of patients with HCC

From: FOXC2 is a prognostic biomarker and contributes to the growth and invasion of human hepatocellular carcinoma

Variables

Univariate

P value

HR

CI (95%)

 

FOXC2 expression (1 = down, 2 = over)

1.772

1.011 ~ 3.107

0.045

Gender (1 = male, 2 = female)

0.433

0.365 ~ 1.034

0.102

Age (1< 50,2 ≥ 50)

0.813

0.341 ~ 1.532

0.352

Serum HBsAg (1 = negative, 2 = positive)

1.537

0.713 ~ 3.811

0.247

Serum AFP (1< 25 ng/ml, 2 ≥ 25 ng/ml)

1.953

1.046 ~ 3.900

0.021

Tumor size (1< 5 cm, 2 ≥ 5 cm)

2.015

1.334 ~ 3.822

0.040

Cirrhosis (1 = Absence, 2 = Presence)

1.151

0.541 ~ 2.388

0.157

Metastasis/Recurrence (1 = no, 2 = yes)

3.71

1.830 ~ 6.043

0.000

UICC stage (1 = I+II, 2 = III + IV)

2.225

1.019 ~ 4.023

0.025

Edmondson grade (1 = High (III/IV), 2 = Low (I/II))

0.911

0.562 ~ 1.831

0.238