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Table 2 Cox regression analysis of patients with HCC

From: FOXC2 is a prognostic biomarker and contributes to the growth and invasion of human hepatocellular carcinoma

Variables Univariate P value
HR CI (95%)  
FOXC2 expression (1 = down, 2 = over) 1.772 1.011 ~ 3.107 0.045
Gender (1 = male, 2 = female) 0.433 0.365 ~ 1.034 0.102
Age (1< 50,2 ≥ 50) 0.813 0.341 ~ 1.532 0.352
Serum HBsAg (1 = negative, 2 = positive) 1.537 0.713 ~ 3.811 0.247
Serum AFP (1< 25 ng/ml, 2 ≥ 25 ng/ml) 1.953 1.046 ~ 3.900 0.021
Tumor size (1< 5 cm, 2 ≥ 5 cm) 2.015 1.334 ~ 3.822 0.040
Cirrhosis (1 = Absence, 2 = Presence) 1.151 0.541 ~ 2.388 0.157
Metastasis/Recurrence (1 = no, 2 = yes) 3.71 1.830 ~ 6.043 0.000
UICC stage (1 = I+II, 2 = III + IV) 2.225 1.019 ~ 4.023 0.025
Edmondson grade (1 = High (III/IV), 2 = Low (I/II)) 0.911 0.562 ~ 1.831 0.238