Fig. 3
From: Adipocytes promote tumor progression and induce PD-L1 expression via TNF-α/IL-6 signaling
Conditional media of 3T3-L1 adipocytes induced PD-L1 expression on HepG2 and B16-F1 cells. a Oil-red O staining and quantification of lipids in 3T3-L1 preadipocytes and adipocytes. Scale bar 10 μm. Data are expressed as mean ± SEM, n = 9, ***P < 0.001 Vs preadipocytes group. b PD-L1 levels of HepG2 cells treated with or without adipocytes conditional media (adi-CM) for 48 h. c PD-L1 levels of B16-F1 cells treated with or without adi-CM for 48 h. Data are expressed as mean ± SEM, n = 6, *P < 0.05 and **P < 0.01 Vs control