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Table 2 Key transcriptional factors (TFs) of five chemokines in SKCM (TRRUST database)

From: Identification of immune-related biomarkers associated with tumorigenesis and prognosis in cutaneous melanoma patients

Key TF Description P-value FDR Regulated genes
IRF7 Interferon regulatory factor 7 7.77E−06 3.09E−05 CCL5, CXCL10
IRF3 Interferon regulatory factor 3 1.24E−05 3.09E−05 CXCL10, CCL5
RELA v-Rel reticuloendotheliosis viral oncogene homolog A (avian) 0.000134 0.000149 CCL4, CXCL10, CCL5
NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.000137 0.000149 CCL5, CXCL10, CCL4
IRF1 Interferon regulatory factor 1 0.000149 0.000149 CXCL10, CCL5