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Fig. 3 | Cancer Cell International

Fig. 3

From: SALL4 promotes gastric cancer progression via hexokinase II mediated glycolysis

Fig. 3

HK-2 is identified as a downstream target of SALL4. a Verification of microarray results for differentially expressed genes between control and SALL4 knockdown MGC-803 cells. b, c Luciferase reporter assays for the relative luciferase activity of HK-2 gene promoter. d ChIP assay for the binding of SALL4 to the promoter region of HK-2 gene. e The changes in levels of hexokinase activity in control and SALL4 knockdown and overexpressing gastric cancer cells. Vertical bars represented SD of the mean values (n = 3); *P < 0.05, **P < 0.01, ***P < 0.001

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