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Fig. 4 | Cancer Cell International

Fig. 4

From: SALL4 promotes gastric cancer progression via hexokinase II mediated glycolysis

Fig. 4

HK-2 mediates the promotion of glycolysis by SALL4 in gastric cancer cells. a, b qRT-PCR and western blot analyzed the expression of SALL4, HK-2 and glycolytic related genes and proteins in SALL4-overexpressing HGC-27 cells and AGS cells with or without HK-2 knockdown. c, d The levels of glucose uptake, lactate production, lactate dehydrogenase activity, ATP level, and hexokinase activity in SALL4-overexpressing HGC-27 cells and AGS cells with or without HK-2 knockdown. Vertical bars represented SD of the mean values (n = 3); *P < 0.05, **P < 0.01, ***P < 0.001

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