Fig. 6

SALL4 knockdown inhibits glycolysis and suppresses gastric cancer growth and metastasis though the downregulation HK-2 in vivo. a, e Representative images of tumors from mice injected with control and SALL4 knockdown MGC-803 cells subcutaneously and intraperitoneally (n = 5 per group). b Representative images of HE staining and immunohistochemical staining of SALL4 and HK-2. c, d, f, g qRT-PCR and western blot analyses of glycolysis-related genes and proteins in tumors from mice injected with control and SALL4 knockdown MGC-803 cells. Vertical bars represented SD of the mean values (n = 3); *P < 0.05, **P < 0.01, ***P < 0.001. Scale bar: 50 μm